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The treatment involves high doses of carnitine, which can then enter cells using another amino acid transporter.[ref] Epigenetic connections: Carnitine and acetylcarnitine also play a role in epigenetics
Granado et al., 2010)

Iwata et al., 1997)

DOX has been linked to the production and accumulation of ROS in the mitochondria, which can damage mitochondrial DNA and impair the activity of the mitochondria 87