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The micelle-water partition coefficient (R mic/wat ), which is the ratio of dye concentration in the micelle and in the surrounding water for a particular surfactant concentration can be written as: This equation can be rewritten using Equation 3: The standard free energy of solubilization (G S ) can be then calculated from the following equation (Equation 7) [51]: where R is the universal gas constant and T is the absolute temperature

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Even its modified version, AOD-9604, failed to produce significant weight reduction in clinical settings

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