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A.HurtadoE.et al

It may increase the need for glutathione and other antioxidant defenses, redirect homocysteine through transsulfuration, impair mitochondrial ATP production, aggravate gut dysfunction, and increase the number of compounds requiring hepatic transformation

Vitamin B-12 is essential for the creation of DNA and the metabolism of cells, and deficiencies in these can lead to anemia, fatigue, muscle weakness, digestive issues, nerve damage, and mood swings

Additionally, both solutions serve overlapping roles as diluents, making it easy to assume theyre functionally interchangeable

Therefore, in the present study, we sought to characterize the liver metabolome after ischemic AKI