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Using spatial transcriptomics, GPX4 has been identified to be located at the interface between the inner cortex and the outer medulla of the kidney, which is the main site of cell ferroptosis after I/R injury

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The GSTF8 gene was also induced by H 2 O 2 through the activation of MPK3/MPK6 kinases (Kovtun et al., 2000) the promoter of which contains an as-1 motif, which is implicated in response to oxidative stress (Garretn et al., The A

Nguyen D, Kantarjian HM, Short NJ, Qiao W, Ning J, Cuglievan B, Daver NG, DiNardo CD, Jabbour EJ, Kadia TM, Borthakur G , Garcia-Manero G, Konopleva MY, Andreeff M, Ravandi-Kashani F, Sasaki K, Issa GC

All participants were given clopidogrel 75 mg daily for the first 21 days and aspirin 100 mg daily for the first 90 days