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6 At our institution, the standard-of-care protocol caps doses at 1 vial of glucarpidase (1000 units) because there is a lack of evidence to prove that higher doses of glucarpidase result in greater clinical benefit
When the synthesized compounds were analyzed for activity against the lipooxygenase enzyme, good results were found
A clear understanding of the mechanisms of renal handling of urate has been hampered by the differences between humans and animal models
Cho CS et al
