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Additionally, it decreased the expression of pro-inflammatory cytokines and inhibited the phosphorylation of STAT3, a key pathway involved in psoriasis pathogenesis [106]

Hameed M, Orrell RW, Cobbold M, Goldspink G, Harridge SDR

What to expect: Systemic benefits like improved skin quality and reduced inflammation often appear within 48 weeks

Immune Support: Strengthens the immune system by neutralizing free radicals and reducing oxidative stress

The clinical effects of these disorders depends on the severity of enzyme deficiency and whether the -glutamyl cycle also is affected in non-erythroid tissues
