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Adverse effects were relatively uncommon, and few serious adverse events including penile hematoma and penile rupture were reported, supporting the overall safety of CCH in the treatment of PD

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VPA induced hepatotoxicity is a welldocumented undesirable effect and can present clinically in different forms such as an asymptomatic and reversible elevation of aminotransferases (alanine transaminase or aspartate aminotransferase), hyperammonaemia with minimal or no liver injury and acute hepatocellular injury with jaundice which can progress to fulminant liver failure

Additionally, it may be a good solution for endurance athletes because it increases muscle strength and endurance and slows down the appearance of lactic acid in the muscles

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