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The relative importance of the various mechanisms regulating glutathione synthesis in different conditions also remains to be established, as does the integration of these controls with changes in transport and degradation
GLP-1 agonists commonly cause nausea, vomiting, and gastrointestinal distress, particularly during dose escalation
However, in Jurkat and some other cell types, the plasma membrane contains an ATP-dependent GSH transport system that is triggered by the initiation of apoptosis
