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In women, the Ovarian-Adrenal-Thyroid (OAT) axis may become unbalanced, producing concurrent symptoms of adrenal strain, estrogen dominance, and subclinical hypothyroidism

Material preparation, data collection and analysis were performed by Ying Xiong, Te Liu, Juan Chen

The reactions catalyzed by both enzymes involve ATP-dependent ligation of an amine group (ammonia or the amino group of cysteine) to the -carboxy group of glutamate

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