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In addition, studies have reported HBx-mediated epigenetic mechanisms contributing to drug resistance

For evaluating smallfiber dysfunction, a frequent contributor to neuropathic pain, microneurography allows direct recording of unmyelinated Cfiber activity and has been instrumental in detecting aberrant nociceptor responses in painful neuropathies [249]

Therefore, the ASD genetic models induced in mice should be established on an identified genetic cause of a disease, reflect key aspects of the human symptoms and respond to pharmacotherapies that are operational in the human diseases (Chadman et al., Genetic animal models of ASD A considerable advancement in detecting the genetic basis of several human diseases has been achieved by geneticists

In addition these cells have been identified as an important stem cell source

10.2307/1590915 [DOI] [PubMed] [Google Scholar] Gross, W