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4.2 AI-driven automated phenotypic recognition and data analytics Manual phenotyping in zebrafish is labor-intensive, subjective, and unscalable: a single 96-well plate generates 18 GB of data requiring 68 h of manual analysis, with high inter-observer variability ( Owing to embryonic transparency, high-throughput capability, and genetic conservation of inflammatory pathways with humans, zebrafish are a powerful model for pharmacodynamic evaluation of natural products

Additionally, it downregulates pro-inflammatory cytokines and ameliorates neuroinflammation in cerebral ischemia/reperfusion injury models [196]

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10.1172/JCI87885 [DOI] [PMC free article] [PubMed] [Google Scholar] Brittenham G

This method streamlines the synthesis process, allowing for the efficient generation of diverse degraders