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Combining organoids and scRNA-seq can identify TMEs and cellular heterogeneity in greater detail, aiding the definition of NNMT functions in different diseases and the development of advanced personalized treatment for patients with metastatic and chemoresistant cancers

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Absorption of vitamin B12 is a complex process requiring adequate stomach acid and intrinsic factor, a glycoprotein produced by gastric parietal cells

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As we have already mentioned, the folate trap can be avoided (through folic acid supplementation, or sometimes through diets high in folate)

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