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Description
Deficiency in B12 can lead to anemia, characterized by fatigue, weakness, and shortness of breath
The liver acts as a reservoir, releasing B12 as needed for metabolic processes
JAMA 321 , 12471248 (2019)
People with lower CYP1A2 activity may generate reactive aflatoxin metabolites more slowly (could be a good thing), but they can still be vulnerable if downstream conjugation pathways (GSTs, UGTs) are also compromised.[ref] Related article: CYP1A2 Gene: Fast or Slow Caffeine Metabolizer and More CYP3A4 and aflatoxin G1 / other mycotoxins: CYP3A4 is involved in the metabolism of aflatoxin G1 and many other compounds, including medications
the overall effect is an improvement in several measures of health
