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However, the metabolic effects it triggers (including HSL activation and lipogenesis inhibition) persist beyond the peptides presence in circulation

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Future studies using chronic or aged animal models will be essential to evaluate prolonged efficacy, dose tolerance, and systemic safety, including potential effects on organ function and histopathology

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lactate dehydrogenase (LDH), of which isoenzymes are found to be specific to astrocytes (LDH5: associated with glycolysis) and neurons (LDH1: associated with oxidative metabolism) (Bittar et al., 2000)