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(PubMed) Berginc K, Milisav I, Kristl A

However, several critical gaps currently limit its translation into clinical practice: (1) the lack of sensitive and standardized biomarkers for early detection of bioenergetic deficits, (2) limited incorporation of creatine profiling into predictive risk models, (3) insufficient personalization of supplementation strategies despite known interindividual variability in transporter function, endogenous synthesis, and tissue kinetics, and (4) underdeveloped clinical validation of advanced creatine formulations and delivery systems
Phase II can be thought of as the garbage truck that picks up the trash and hauls it away
Hai thnh phn cu trc da dng phn t nh, d hp thu

Evans D