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The importance of DAT in dopaminergic signaling was further reiterated by Jones et al

This broad spectrum of manifestations reflects the complexity of its pathophysiology, which involves a combination of dopaminergic neuron loss, oxidative stress, alpha-synuclein aggregation into Lewy bodies, mitochondrial dysfunction, neuroinflammation, and disruptions in the gut-brain axis 5,6,7,8,9

My migraines decreased about 20 percent after that first month