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Metabolic trajectories in NHP are dose dependent Cohort 2: NHP serum (5.8 Gy and 7.2 Gy) Both LCMS and NMR, and all 5.8 Gy and 7.2 Gy time points [8 hours (8H), day 2 (D2), day 3 (D3), day 8 (D8)] were modeled with PLS against the baseline norm of 7 days prior to irradiation (D-7)

Arch Neurol 59(10):15411550 Smith KM, Matson S, Matson WR, Cormier K, Del Signore SJ, Hagerty SW et al (2006) Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntingtons disease mice