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Second, ascorbic acids reduction efficiency is unstable because of oxidation in light and air, S -alkylation reagents were used to irreversibly and specifically bind SNO bonds, form S -alkylated biotin proteins, and enhance the recognition efficiency of SNO-modified proteins [80]

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doi: 10.1016/j.canlet.2011.12.012 4 DelaneyGJacobSFeatherstoneCBartonM

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