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Analysis of the double mutants lacking glutathione or thioredoxin suggested that theses antioxidant molecules are not responsible for compensating in vivo the absence of CgCta1.10 To date, the role of CgCta1 as a virulence factor has not been established as in other pathogenic fungi.8 Superoxide dismutases SODs are metalloenzymes that catalyze the dismutation of O2 into H2O2 and oxygen

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In conclusion, our results suggest that SAG administration protects the liver from CCl4 intoxication by restoring the oxidative balance, ameliorating the impairment of mitophagy and leading to reduced inflammation

Engebretson, S

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