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From our H-C-T-P network and docking results it was found that the compounds like Gamma-Tocopherol, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl) ethyl ester, Benzenepropanoic acid, 4-hydroxy-, methyl ester, 1,3,4,5-Tetrahydroxycyclo-hexanecarboxylic acid can interact with the AKT1 and can inhibit it

While conventional treatments, such as intensive glucose lowering and strict blood pressure control, can slow the decline in kidney function, they do not prevent the progression of renal failure

doi: 10.1016/j.cellsig.2005.11.007

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