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A follow-up study of this cohort recently showed that in the long run total thyroid ablation was no better than total thyroidectomy alone, although it was associated with a prompter achievement of the best possible result obtainable by medical treatment and with an earlier possibility to submit the patient to rehabilitative surgery (147)

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The rats were anesthetized by intraperitoneal injections of ketamine (100 mg/kg) and xylazine (10 mg/kg) followed by decapitation