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doi: 10.4236/jcdsa.2021.114029 37
GCLM (/)/hSOD1 WT mice do not spontaneously form tumors, their prepared fibroblasts exhibit elevated levels of ROS and DNA damage and upregulated levels of Tp53 and p21 (Hayes et al., 2020)
C9orf72 ALS/FTD-associated poly (GR) 80 DPRs interact with Atp5a1, which compromises mitochondrial functions in mice due to increased ROS production (Choi et al., 2019)
Bottom line Existing evidence comparing oral with IM vitamin B12 is suboptimal
Regression of Aflatoxin B1-Induced Hepatocellular Carcinomas by Reduced Glutathione
