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Clinical evidence indicating accelerated antidepressant response, improved cognition, enhanced sleep architecture, and reduced biomarkers of neuronal injury in elderly and medically comorbid populations underscores its relevance in late-life depression and depression associated with cognitive or vascular dysfunction (96)

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While Met carriers may produce less activity-dependent BDNF, they still respond to exercise and other BDNF-boosting interventions

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Differential Expression of Glutamate Dehydrogenase in Cultured Neurons and Astrocytes From Mouse Cerebellum and Cerebral Cortex. Journal of Neuroscience Research 66: 909913

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Blood 96(11):727a, 2000

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