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The first committed step, which is catalysed by G6PD, generates an initial NADPH molecule

Folate, which is present in foods as a polyglutamate conjugate, undergoes hydrolysis in the intestinal mucosa to its monoglutamate form, which serves as the transport form of folate (Figure 1)

doi: 10.1038/s41395-018-0098-4

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[DOI] [PubMed] [Google Scholar] 34.Mazzieri A., Montanucci P., Basta G., Calafiore R
