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Oxidative stressan imbalance between free radicals and antioxidants in your bodyand low amounts of vitamin E and alpha-lipoic acid can cause glutathione levels to decline

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Science says that glutathione is an effective answer.Glutathione not only decreases the melanin (pigmentation) in your skin but has also been found to decrease wrinkles and increase skin elasticity.Glutathione works on the skin pigment production by inhibiting tyrosinase, an enzyme involved in making melanin.In one study, both GSH and GSSG achieved a skin lightening effect - though it takes a few weeks to develop

They expect modifying the production of ROS to have potential for developing new treatments.