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It mimics endogenous GLP-1 with 94% homology but with extended half-life (~165 hours) due to albumin binding via a C-18 fatty di-acid side chain

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Chemotherapy-induced peripheral neuropathy CIPN involves direct neurotoxic damage to dorsal root ganglion neurons, primarily through mitochondrial dysfunction, disrupted axonal transport, and neuroinflammation

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Casgevy and Lyfgenia: two gene therapies for sickle cell disease

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