cysteine short peptide glutathione Frontiers Glutathione Synthase - an overview

410 In acidic environments, the elevated proton concentration increases the hydrophobicity of peptides

5,81 Adverse effects reported with chlorambucil use include myelosuppression, hepatopathy, Fanconi syndrome and myoclonus

The agent can be selectively activated by GSH to generate reactive alkoxyamine that traps AP sites in cancer cells

For example, research into the role of matrix metalloproteinases (MMPs), enzymes that degrade extracellular matrix components, provides insights into how excessive MMP activity might contribute to ligament degradation and injury risk

Detailed signaling mechanism still remains to be elucidated