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Wu Q, et al

Relationship to the GH-IGF-1 Axis Because this fragment does not appear to stimulate IGF-1 production in laboratory models, it provides researchers with a tool to study the IGF-1-independent aspects of GH signalling in metabolic biology

Nrf2 regulates various antioxidant enzyme systems including peroxiredoxin (Prdx), superoxide dismutase (SOD), catalase (CAT), thioredoxin (Trx), sulfaredoxin (Srx), glutathione peroxidase (Gpx), glutathione reductase (GR), NAD(P)H quinone oxidoreducase (Nqo1) and heme oxygenase 1 (HO-1) and Ferritin

However, it's important to check with the manufacturer for any additives or stabilizers used in the injection solution

Overall, neuroprotective compounds' clinical development is challenged by a consistent lack of clinical efficacy resulting in dozens of failed clinical trials over the past 3 decades [6]