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Neuroinflammation is a major cause of ALS and other neurodegenerative diseases

48 Furthermore, BCAAs are essential for the proper function of immune cells in the immune system, promoting lymphocyte proliferation and cytotoxic T-cell activation through the oxidative decomposition of dehydrogenase and decarboxylase expressed by immune cells

Acknowledgements Funding for this study was provided by the National Natural Science Foundation of China (82388101, 22375127), the Shanghai Commission for Science and Technology (Grant No

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both are downstream consequences of the same systemic glutathione depletion and unchecked oxidative stress