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Present in human plasma, its concentration decreases with age
Neurology 69, 16961700.10.1212/01.wnl.0000279518.10072.df 10 AmesB
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This triggers sequential conformational changes that lead to the transition of hemoglobins quaternary structure, which binds two oxygen molecules, Hb(O 2 ) 2 , from the T state to the R state
Oxidative stress promotes permeability of the blood-brain barrier: implications for the pathogenesis of Alzheimer's disease
