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Besides, overactivation of ACSL4 and LOXs can also convert PUFAs into lipid peroxide
The upregulation of GPx2 triggers the activity of the Wnt pathway and enhances the dismutation of hydrogen peroxide, the inhibition of apoptosis, and the alleviation of oxidative stress
Fent, K
Interestingly, an emerging body of evidence suggests that micro RNAs (miRNAs, small non-coding RNAs involved in the post-transcriptional regulation of gene expression) could be putative biomarkers for detecting neurodegeneration Thus, recent reviews have shown that some miRNAs are differentially associated with AD by modulating the expression of important genes involved in A production (e.g., BACE1 ) or inflammation (Goodall et al., 2013
International Journal of Molecular Sciences, 22 (19), 10376.
