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Heme-driven production of ROS is involved in the pathophysiology of several disorders by damaging lipid membranes (Su et al., 2019), proteins (Pilo et al., 2022) and nucleic acids (Carter et al., 2022), activating inflammatory pathways (Wei et al., 2024), and perturbing membrane channels (Miranda et al., 2023), among other toxic effects

The study provides a specific targeting technique for colorectal cancer and can also be implemented in other cancers as a complex nanotheranostics technique that accounts for TME reprogramming ( As discussed previously, a plethora of research studies elaborating on different forms of nanodelivery system developed for cancer nanotheranostics have been conducted

This resulted in all subscales having a minimum score of 0 and a maximum of 1

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Sensitivity to oxidation can also be monitored by measuring the antioxidative capacity of a product