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Once the mutation has been detected by host immune system, various lymphocytic infiltrates would accumulate in and around tumor zones to harbor intrinsic and adaptive immunities [3]

Generally well-tolerated in human trials at research doses with no major safety concerns reported [19]

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doi: 10.1111/j.1538-7836.2004.00845.x 41 ShioseSHataYNodaYSassaYTakedaAYoshikawaHet al

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