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While clinical and experimental studies implicate many neurotransmitters in epileptogenesis, the dopaminergic system plays a prominent role in the modulation of seizures

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We discuss underlying pathophysiological mechanisms, risk factors, and clinically relevant biomarkers, as well as prevention strategiessuch as rigorous blood pressure (BP) control and close monitoring of coagulation parameters

One study using the PST model in rats revealed downregulation of GLT-1 and GLAST in the spinal cord as early as 1 days post-PST and persisted for at least 21 days

Endoplasmic reticulum stress and oxidative stress in cell fate decision and human disease