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It was shown roflumilast reduced the diffuse emphysema induced by CS in mice as compared with that in the control group
Neuron 41 , 535547 (2004)
Nature Chemical Biology, 6: 140147
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The clarified lysates were loaded onto CAQK-coated Sulfolink-agarose beads (Pierce) and incubated at 4 C for 34 h
