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Increased oxidative stress in autism may be due to (a) increased production of oxidative markers or (b) increased exposure to environmental pro-oxidants, or (c) deficiencies of antioxidants (ceruloplasmin, transferrin, SOD, GPx, catalase, reduced glutathione), impaired energy metabolism (NAD + , NADH, ATP, pyruvate, and lactate), and abnormal tryptophan catabolism

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Some people claim that supplemental GABA has a calming effect on them, possibly due to changes via the gut-brain axis.[ref] You may want to try supplemental GABA if you have gut issues