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(3) HA is portrayed as a significant component of skin cells, noted for its moisture-binding potential and actions on cell proliferation and inflammation, with different molecular weights (LMW and HMW) showing distinct biological activities

That substance was a protein, and from it, they identified a smaller substance that they believed was the active principle, or the part of the protein responsible for producing the therapeutic benefits

Genet Med 22 , 15761582 (2020)
FDA Warning Letter to Harry D
SAG has the ability to penetrate the mitochondrial membrane, helping to maintain its integrity and function