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Synechocystis synthesises B 12 via the anaerobic pathway and cbiE mutants, which will accumulate B 12 -precursors prior to cobalt-precorrin 7, demonstrate altered expression of coaT [94]

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This implies that MTH1 may contribute to the heightened 8-oxoGsn levels in cardiomyocytes, thereby exacerbating damage to these cells ( 3.2 MTH1 role in neurological diseases Oxidative stress is a significant risk factor for Alzheimers disease (AD), with notable accumulation of 8-oxo-7,8-dihydroguanine (8-oxoG), an oxidized form of guanine, observed in AD brains