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doi: 10.1002/ams2.501
MOTS-c not only functions as a cell-autonomous peptide but also affects a number of pathological metabolic processes in the body by acting similarly to a hormone, including insulin resistance reduction, obesity prevention, muscle function improvement, bone metabolism promotion, immune regulation enhancement, and aging postponement
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The GLP-1R affinity of semaglutide (0.38 0.06 nM) was three-fold decreased compared to liraglutide, whereas the albumin affinity was increased
