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Optimization of a privileged structure leading to potent and selective human melanocortin subtype-4 receptor ligands

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Key points A novel lipase (Lac-Rh) was isolated from Lacticaseibacillus rhamnosus IDCC 3201 Purified Lac-Rh exhibited its highest activity at a temperature of 60 C and a pH of 8, respectively Lac-Rh remains stable in commercial laundry detergent and enhances washing performance Similar content being viewed by others Introduction Triacylglycerol hydrolases, or lipases (EC 3.1.1.3), are an essential class of enzymes which can catalyze a variety of processes, such as esterification, interesterification, transesterification, and hydrolysis of carboxylic ester bonds (Chandra et al

Furthermore, free plasma LCR levels at week 9 were higher in the LCR group (7.04 mol/L, 95% CI 3.74, 10.3) than in the PLA group (0.13 mol/L, 95% CI -3.31, 3.57)

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