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However, the side effects are mostly mild

Supplementary material The Supplementary Material for this article can be found online at: References 1 AchudumeA

10.1186/s12933-018-0680-5 49 GuanY.WangD.BuH.ZhaoT.WangH

It was found to be moderately elevated (5.10 1.37) in comparison to the normal group, which showed minimal collagen deposition (as indicated by the faint blue color) and a very low score (0.30 0.48), which confirms a significant deviation and damage to the structural integrity of the lung (P = 0.0001) as shown in [Fig

Moreover, H 2 O 2 -mediated apoptosis plays a critical role by activating apoptosis signal-regulating kinase 1 (ASK-1) [423,424]