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There are some oxidoreductases, whose activity depends on proximal histidine-asparagine interactions (e.g

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Additionally, a recent study (198) suggests that R-SH, an OSM, could serve as a biomarker for IBD, proving more sensitive than C-reactive protein (CRP) in detecting moderate endoscopic activity, though less sensitive than fecal calprotectin, with age and albumin levels as potential confounding factors, and indicates that R-SH may improve IBD monitoring