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Acute COVID pathophysiology linked to the cytokine storm and oxidative stress, and long COVID research have yielded mitochondrial dysfunction among other mechanisms, all of which can be alleviated by providing melatonin (17)

10.1016/j.phytochem.2011.02.025 Phytochemistry 3 AstierJ.LindermayrC

Mol Neurodegener 15:122 Pszczoowska M, Walczak K, Mikw W, Mroziak M, Chojdak-ukasiewicz J, Leszek J (2024) Mitochondrial disorders leading to Alzheimers diseaseperspectives of diagnosis and treatment
Paz-Linares, A
In contrast, Gpr17 activation in oligodendrocyte lineage cells impairs myelination