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Gain-of-function mutant p53 in cancer progression and therapy

It was early, but the lack of records threatened disaster for Enhanced

[DOI] [PMC free article] [PubMed] 357.Lambeth, T

Cytotoxicity was assayed by determining the percentage of cell viability (with respect to unexposed cells) using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) 47 method, which correlates the cellular metabolic activity with the number of viable cells in culture

Such rhythms still persist in constant darkness (free-running conditions), and can be reset by exposure to external signals including light (entrainment)
