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and Chung K

Nat Commun 15, 2053

To test whether the MTS pathway was supporting the TR/GR-null livers, we treated mice with single-dose challenges by inhibitors of cystine uptake (sulfasalazine, SSZ), possible cysteine uptake (2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid, BCH), conversion of methionine into cysteine by MTS (propargylglycine, PPGG, which inhibits trans -sulfuration and not the methionine cycle), or synthesis of GSH (BSO) 11

National Institutes on Aging and the National Cancer Institute (AG004020 and CA152559), the Montana Agricultural Experiment Station, as well as support from the College of Agriculture and the Department of Microbiology and Immunology at Montana State University to EES

QL: Writing original draft
