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Zinc Deficiency: Regular use of glutathione can result in reduced zinc content in the body

This model suggests that, beyond TG accumulation and inflammation, additional interrelated mechanisms such as lipotoxicity, endoplasmic reticulum (ER) stress, mitochondrial dysfunction, and inflammasome activation collectively contribute to the development and progression of MASLD

Additionally, men may have greater plasma homocysteine levels due to hormonal influences, particularly testosterone

After receiving 28 days of treatment, different dose groups of ZSP601 showed significant improvements in metabolism, hepatic fat content, inflammation and fibrosis biomarker indices (262), supporting the evaluation of its long-term safety and efficacy in a larger sample size of MASH patients