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Rodent studies show this decline ranges from 15-65% in skeletal muscle and 10-50% in liver tissue

It also helps your metabolism work more efficiently, which increases energy and supports weight loss

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Endogenous causes (medical conditions) When B12 is elevated without supplementation , it can indicate that the body is releasing stored B12 from damaged tissues, producing excess B12-binding proteins, or failing to clear B12 normally

This is a game-changer for metabolic health, as research shows that this process can increase NAD+ levels in fat cells, supporting more efficient energy use and fat oxidation