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The percentage of Ki67 + cells in the basal layer of the epidermis and in the outer root sheath of hair follicles, and the number of vessels per mm 2 were calculated according to morphometric criteria [18]

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who demonstrated that patients with SSc-ILD who receive both pirfenidone and immunosuppressants have a statistically significant improvement in FVC at 24 weeks compared to patients receiving only immunosuppressants (56)

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