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Homocysteine, Folate, and Nonalcoholic Fatty Liver Disease: A Systematic Review with Meta-Analysis and Mendelian Randomization Investigation

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Bramham CR, Panja D

Specifically, DNA methylation decreases globally with age [53, 95], but simultaneously increases in CpG islands [96,97,98,99]
Vitamin D additionally may enhance heme oxygenase-1 and GPX4 expression and reduces ferroptosis in aging brains (99), collectively mitigating oxidative stress and neuroinflammation
