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Healthcare organizations and researchers have identified natural, effective, and sustainable weight loss methods

AOD9604 is a synthetic 15amino acid peptide fragment derived from the Cterminal region of human growth hormone (amino acids 176191)
Adequate protein intake, biotin supplementation, and avoiding excessively rapid weight loss (more than 2-3 pounds per week) reduce the risk

Moreover, when mitophagy is triggered by membrane potential dissipation, PGAM5 is also cleaved by the rhomboid protease PARL, which facilitates the interaction between PGAM5 and FUNDC1 in a Syntaxin-17 (SYN17)-dependent manner [111]